MALIGNANT MIGRATING PARTIAL SEIZURES OF INFANCY (MMPSI)
MMPSI is part of our Childhood Epilepsy Panel (NGS). Click here to access a complete list of the genes covered in this panel.
MMPSI is an early form of infantile epileptic encephalopathy. Seizure onset peaks between the first and third month of age.
The seizures can become almost continuous and occur in clusters of 5 to 30 seizures every day, or throughout a few days in a row. The clinical features may vary, but include eye deviation and jerking (also in the limbs), eyelid twitching, salivation or apnea; subclinical (unseen) or clinically mild seizures may also appear.
This condition has a negative effect in the child's development and the general deterioration becomes evident. Infants can lose almost all abilities and only seem to improve in seizure-free periods. There is progressive microcephaly. However, a few patients can improve if seizure freedom is achieved.
All of Amplexa's neurology tests can be found in our Neurology Brochure.