AUTOSOMAL DOMINANT LATERAL TEMPORAL LOBE EPILEPSY (ADLTE)
ADLTE is part of our Childhood Epilepsy Panel (NGS). Click here to access a complete list of the genes covered in this panel.
Autosomal dominant lateral temporal epilepsy (ADLTE) is an inherited epilepsy syndrome with typical onset in adolescence or early adulthood, although age of onset may vary greatly. In 50% of the cases, the condition is related to a mutation in the LGI1 gene.
ADLTE patients can present focal seizures associated with auditory stimuli triggers, originating from the lateral temporal lobe cortex, occassionally becoming generalised. Auditory auras, related to this part of the brain, are common. Additionally, other types of non-auditory auras may appear.
All of Amplexa's neurology tests can be found in our Neurology Brochure.